maluTeinizirebeli hormoni

maluTeinizirebeli hormoni warmoadgens hipofizis hormons, romelsac gamoimuSaveben gonadotropuli ujredebi. maluTeizinirebeli hormonis sinonimebia lutropini, luTrofini, LH. maluTeinizirebeli hormoni sinTezirdeba adeno hipofizSi da monawileobas Rebulobs adamianis reproduqciuli sistemis normalur funqcionirebaSi. maluTeizinirebeli hormonis warmoadgens ovulaciis gamSveb meqanizms (trigers), misi didi raodenobiT gamomuSaveba xdeba ovulaciis periodSi, Sedegad yalibdeba yviTeli sxeuli, romelic qalis organizmSi progesteronis mniSvnelovan wyaros warmoadgens da sasicocxlosd mniSvnelovania ganayofierebuli kvercxujredisTvis da SemdgomSi embrionisTvis – orsulobisTvis. mamakacebSic gamomuSavdeba maluTeizinirebeli hormoni oRond aq cota sxva datvirTva aqvs. mas mamakacebis SemTxvewvaSi zogjer interstitial cell-stimulating hormone (ICSH) -sac eZaxian. mamakacebSi es homoni astimulirebs leidingis ujredebs da testosteronis sinTezs ganapirobebs.

maluTeizinirebeli hormoni struqturulad heterodimerul glikoproteins warmoadgens. misi masinTezirebeli genebi meeqvse qromosomiaze mdebareoben.

qalebSi: maluTeizinirebeli hormoni astimulirebs Teka ujredebs, romlis Sedegadac sinTezirdeba androgenebi – aq estradiolisTvis qalis sasqeso hormonisTvis prekursors warmoadgens. SemdgomSi folikulo mastimulirebeli hormonis gavleniT granuloza ujredebis proliferacia da estrogenebis sinTezis gaZliereba mimdinareobs.

sabolood, rodesac folikuli momwifdeba da estrogenebis sinTezi piks miaRwevs, maSin uaryofiTi kavSiri hipoTalamusTan icvleba dadebiTi ukukavSiriT. rac imiT gamoixateba, rom maluTeinizirebeli hormonis Semcirebis nacvlad, piriqiT, misi didi raodenobiT gamomuSaveba stimulirdeba. maluTeizinirebeli hormonis gamomuSaveba ase pulsurad da Zlierad grZeldeba 24-48 saaTis ganmavlobaSi. Sedegad xdeba ovulacia. folikulidan gamoTavisufldeba kvercxujredi, xolo Tavad folikuli gadaiqceva yviTel sxeulad, romelic SemdgomSi progesteronis sinTezs iwyebs, romelic saSvilosnos