pss (nawili II)

policisturi sakvercxis sindromi.

policisturi sakvercxis dros xSirad naCvenebia klasikuri aTerogenuli cximovani profili : momatebuli dabali simkvrivis lipoproteinebi (LDL), saerTo qolesterini, Semcirebulia maRali simkvrivis lipoproteinebis (HDL) raodenoba.
policisturi sakvercxis sindroms axasiaTebs cximebis gadanawileba mamakacuri tipiT.

policisturi sakvercxis sindromis Sedegi SeiZleba iyos: endometriumis simsivnis riskis momateba, unayofoba (80-90%), orsulobis spontanuri Sewyveta.
diagnozi da diferencialuri diagnozi:
• policisturi sakvercxis sindromi – testosteroni – momatebulia. dihidroepiandrosteron sulfati – SeiZleba iyos mcired momatebuli. maluTeizebeli hormonis da folikulomastimulirebeli hormonis fardoba- ZiriTadad 2:1 ze metia.
oligo-anovulaciis mizezebi:
• hiperTiroidizmi – Tireo mastimulirebeli hormoni TSH – daqveiTebulia.
• hipoTiroidizmi – Tireo mastimulirebeli hormoni TSH – momatebulia.
• hiperprolaqtinemia – prolaqtinis done – momatebulia
• hipogonadotropuli hipogonadizmi – FSH, LH, E2 – yvela daqveiTebulia.
• sakvercxeebis naadrevi ukmarisoba – gonadotropinebi – daqveiTebulia
hiperandrogeniis mizezebi:
• Tirkmelzeda jirkvlis Tandayolili hiperplazia – 17-OH-P > 200ng/dl.
• kuSingis sindromi – kortizoli – momatebulia
mkurnaloba:
• dakvirveba -Tu qals aqvs pss, Tumca aqvs regularuli cikli 8-12 cikli wlis ganmavlobaSi, msubuqi hiperandrogenizmi SesaZloa ar iqnes namkurnalevi da arCeuli iqnas dakvirvebis taqtika.
• wonis dakleba – hipokaloriuli balansirebuli dieta.
• varjiSi – kviraSi minimum 150 wuTi varjiSia saWiro.
• kombinirebuli oraluri kontraceptivebi – awesrigebs cikls, amcirebs gonadotropinebis gamoyofas, amcirebs androgenebis produqcias (sakvercxeebis mier), estrogenebis antagonisturi moqmedeba aqvs progestins endometriumTan mimarTebaSi.
• 5 alfa reduqtazas inhibitorebi – finasteridi (Proscar , Propecia, 5-mg daily)