policisturi sakvercxis sindromi (nawili I )

mimarT>
insulin-rezistentoba asocirebulia ramodenime daavadebasTan: Saqriani diabeti tipi 2 , hipertenzia, dislipidemia, kardiovaskularuli daavadebebi.
policisturi sakvercxis sindromi iwvevs:
• iregularul menstrualur cikls;
• hirsutizmi/akne/alopecia;
• unayofoba;
• metaboluri darRvevebi;
• lipiduri profilis darRveva/glukozisadmi tolerantobis darRveva.
• simsuqne
Soreuli garTulebebi:
• Saqriani diabeti;
• gul-sisxlZarRvTa daavadebebi;
• endometriumis simsivne.
insulini da maluTeizebeli hormoni astimulirebs Teka ujredebSi androgenebis sinTezs. Sesabamisad testosteronis da androstendionis raodenoba imatebs. gansakuTrebiT imatebs Tavisufali testosteronis raodenoba qalebis 70-80 % Si. 25-65 % Si momatebulia dihidroepiandrosteronis raodenoba. amasTan erTad SesaZloa momatebuli iyos estronis raodenoba rac androgenebis periferiul gardaqmnas ukavSirdeba (aromatazas meSveobiT).
sasqeso hormonTan SekavSirebuli globulini – policisturi sakvercxis sindromis dris xSirad aRiniSneba sasqeso hormonTan SekavSirebuli globulinis donis daqveiTeba. am cilebis produqcia xdeba RviZlSi da mis sinTezs amcirebs insulini, androgenebi, kortikoidebi, progesteroni da zrdis hormoni. SemboWveli cilebis Semcirebis gamo izrdeba Tavisufali androgenebis raodenoba. amitomac zog SemTxvevaSi testosteronis saerTo raodenoba normaluria, Tumca Tavisufali testosteronis done gazrdili.
miuxedavad imisa, rom policisturi sakvercxis sindromis dros momatebulia androgenebis raodenoba, daqveiTebulia progesteronis done anovulaciis gamo. ZiriTadi mizezi rac anovulacias iwvevs ucnobia, Tumca maluTeizebeli hormonis maRali done iwvevs menstrualuri ciklis regularobis darRvevas. zog SemTxvevaSi anovulacia ganpirobebulia insulin rezistentobiT, amitomac pacientebis nawilSi cikli aRdgeba meTforminiT mkurnalobis dros.
policisturi sakvercxis sindromis dros ZiriTadi Civilebia:
menstrualuri ciklis darRveva
SeiZleba iyos gamoxatuli amenoreiT, oligomenoreiT, epizoduri